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Anton Simulations Reveal How Alzheimer’s Fibril Growth May Accelerate

Anton Simulations Reveal How Alzheimer’s Fibril Growth May Accelerate

by Ken Chiacchia | Oct 22, 2024 | Anton, Anton 2, Research, Science Highlights

With Alzheimer’s disease, amyloid peptides combine to form fibrils, in turn forming plaques around neurons. Adobe Stock 421239213 Unexpected Way for Amyloid Peptides to Join Fibrils Explains Time Lag, then Accelerated Growth, in Fibril Formation and Disease...
$3.15 Million from NIH to Fund Operation of Third-Generation Anton Supercomputer at Pittsburgh Supercomputing Center

$3.15 Million from NIH to Fund Operation of Third-Generation Anton Supercomputer at Pittsburgh Supercomputing Center

by Ken Chiacchia | Aug 5, 2024 | Anton, Anton 3, COVID-19, News, Press release, Resources, Systems

Designed and Built by D. E. Shaw Research, System Will Simulate Biomolecules Roughly 100 Times Faster than General-Purpose Supercomputers A third-generation Anton supercomputer (Anton 3), developed by D. E. Shaw Research (DESRES), will soon arrive at the Pittsburgh...
Anton Simulations Explain Delay in CRISPR-Cas12a’s DNA-Cutting Function

Anton Simulations Explain Delay in CRISPR-Cas12a’s DNA-Cutting Function

by Ken Chiacchia | Jul 31, 2024 | Anton, Anton 2, Research, Science Highlights

Scientists used the second-generation DESRES Anton supercomputer hosted at PSC to show how a critical protein for furture gene therapy pauses before completing its cutting of a target DNA. Credit: Aakash Saha Understanding Unexpected Motion of Protein Will Be Crucial...
Anton 2 Simulations Explain Mechanism for Loading DNA into Virus

Anton 2 Simulations Explain Mechanism for Loading DNA into Virus

by Ken Chiacchia | Sep 27, 2021 | Anton, Anton 2, Science Highlights

Anton 2 Simulations Explain mechanism for Loading DNA into Virus   Two-phase Motor Packages DNA into Viral Capsids, May Offer Drug Target To cause disease, viruses must package their DNA into new virus particles to infect more cells. An important step—and...

Protein Research Leaps Forward with Anton at Pittsburgh Supercomputing Center

by Ken Chiacchia | Jul 21, 2011 | 2011Press, Anton, Anton 2, Science Highlights

Protein Research Leaps Forward with Anton at Pittsburgh Supercomputing Center Special-purpose supercomputer’s stay is extended, with new round of time allocations PITTSBURGH, July 21, 2011 — Using a special-purpose supercomputer for biomolecular simulation, U.S....

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